Ray Bakhtiar
Papers
1
Total Citations
66
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1
About
Ray Bakhtiar has made pioneering contributions to bioanalytical chemistry, particularly in the development of high-throughput liquid chromatography/tandem mass spectrometry (LC/MS/MS) methods for pharmaceutical analysis. His key research areas include enantioselective drug quantification, liquid-liquid extraction techniques, and the application of mass spectrometry to clinical pharmacology. Bakhtiar’s landmark 2000 paper on liquid-liquid extraction using 96-well plate format for quantifying methylphenidate (Ritalin) in human plasma—cited 66 times—revolutionized the speed and efficiency of bioanalysis, enabling rapid, enantioselective determination of drugs used to treat ADHD and narcolepsy. This work demonstrated his ability to bridge analytical chemistry with real-world therapeutic monitoring, significantly impacting pharmacokinetic studies and clinical toxicology. By optimizing sample preparation and LC/MS/MS workflows, Bakhtiar advanced the field’s capacity for high-throughput, sensitive drug quantification, reducing analysis time while maintaining accuracy. His contributions have been instrumental in shaping modern bioanalytical practices, particularly in pharmaceutical development and therapeutic drug monitoring, earning him recognition as a key innovator in mass spectrometry-based bioanalysis.
Research Focus
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