Odd Geiran

About

Odd Geiran is a leading researcher in the molecular genetics of Marfan syndrome (MFS), a heritable connective tissue disorder. His work has been pivotal in advancing the understanding of genotype-phenotype correlations in this monogenic condition. In a landmark 2007 study, he systematically searched for links between *FBN1* genotype and the complete Ghent phenotype in 44 unrelated Norwegian patients, a key contribution that has garnered 34 citations. This work underscores the clinical promise of predictive genetic testing for prognosis and tailored follow-up. Geiran also pioneered a rapid, efficient strategy for *FBN1* mutation detection, combining automated sample preparation with direct sequencing as the primary approach. Published in 2006, this method addressed the immense challenge of screening the gene’s 65 exons and has been cited 20 times for its practical impact on diagnostics. By enabling more accessible and reliable mutation identification, Geiran’s research has directly supported the clinical management of MFS and related fibrillinopathies, solidifying his reputation as a key figure in the field.

Research Focus

Key Achievements

Top Papers

1. 1
   Search for correlations between <i>FBN1</i> genotype and complete Ghent phenotype in 44 unrelated Norwegian patients with Marfan syndrome

   34 citations · 2007
2. 2
   Rapid and Efficient <i>FBN1</i> Mutation Detection Using Automated Sample Preparation and Direct Sequencing As the Primary Strategy

   20 citations · 2006

Key Collaborators

Contact & Links