Nicholas van As

National Health Service, Royal Marsden NHS Foundation Trust

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About

Nicholas van As is a leading clinical researcher in the field of urological oncology, with a primary focus on the management of prostate cancer. His work addresses the critical challenge of balancing effective cancer control with the minimization of treatment-related side effects. Van As is perhaps best known for his contributions to the Pace Study (Prostate Advances in Comparative Evidence), where his research demonstrated successful patient acceptance of randomization in clinical trials, a vital step for generating high-quality comparative evidence. His most cited work, "The contemporary management of prostate cancer" (2025, 24 citations), provides a comprehensive overview of the field, highlighting the expected doubling of global incidence and mortality over the next two decades and the lack of strong environmental associations, underscoring the urgency for improved treatment strategies. Through his rigorous clinical trial design and patient-centered research, van As has significantly advanced the evidence base for prostate cancer care, influencing both clinical practice and future research directions.