Mignon L. Loh
Papers
1
Total Citations
2
H-Index
1
About
Dr. Mignon L. Loh is a leading pediatric hematologist-oncologist whose research focuses on the genomic drivers and targeted therapies for high-risk childhood leukemias, particularly acute lymphoblastic leukemia (ALL). Her work has been instrumental in characterizing rare, treatment-resistant subtypes, such as TCF3-HLF-rearranged ALL. In a landmark 2018 study, Dr. Loh and her team demonstrated significant in vivo sensitivity to Aurora kinase inhibition in this aggressive leukemia, offering a promising therapeutic avenue for a disease with historically dismal outcomes. While this specific paper has garnered 2 citations, her broader body of work—including leadership in the Children’s Oncology Group and pivotal studies on RAS pathway mutations and Ph-like ALL—has amassed thousands of citations, shaping standard-of-care protocols worldwide. Dr. Loh’s contributions extend beyond the lab; she is a dedicated mentor and advocate for translating genomic discoveries into clinical trials, earning her recognition as a Doris Duke Clinical Scientist Development Award recipient. Her relentless pursuit of cures for the most challenging pediatric cancers continues to inspire the next generation of physician-scientists.
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Top Papers
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