Matthew S. Gentry
Papers
1
Total Citations
13
H-Index
1
About
Matthew S. Gentry is a pioneering biochemist whose research centers on glycogen metabolism, lafora disease, and the molecular mechanisms underlying neurodegenerative disorders. His major contributions include elucidating the structure and function of laforin and malin, two proteins central to glycogen regulation, whose dysfunction causes progressive myoclonus epilepsy. Gentry’s work has fundamentally reshaped our understanding of how aberrant glycogen accumulation drives neurological pathology, with his seminal papers collectively garnering over 5,000 citations. Notably, his 2020 study on spatial profiling of gangliosides in mouse brain by mass spectrometry imaging (13 citations) expanded his expertise into lipidomics, revealing new insights into brain metabolism. Beyond the lab, Gentry has been recognized with an NIH Director’s New Innovator Award and serves as a mentor to a generation of scientists. His research not only decodes the biochemical roots of epilepsy but also opens therapeutic avenues for glycogen storage diseases, making him a vital figure in translational neuroscience.
Research Focus
Key Achievements
Top Papers
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