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About

Marlene Fischer is a leading anesthesiology researcher whose work focuses on the intersection of surgical positioning, cerebral hemodynamics, and postoperative cognitive outcomes. Her key research areas include cerebral autoregulation during surgery, postoperative delirium, and cognitive function following robot-assisted versus open surgical procedures. Fischer’s major contributions center on demonstrating how the extreme Trendelenburg position used in robot-assisted radical prostatectomy can compromise cerebral autoregulation and potentially increase the risk of postoperative cognitive decline. Her landmark 2020 study on positioning and cerebral autoregulation (20 citations) established critical safety considerations for anesthesiologists managing patients in steep head-down tilt. In related work, she compared cognitive function between robot-assisted and open prostatectomy (16 citations) and investigated postanesthesia care unit delirium rates (14 citations), providing evidence that surgical approach and positioning significantly impact early postoperative neurological outcomes. Fischer’s prospective observational studies have been instrumental in advancing perioperative neuroprotection strategies, making her research essential reading for anesthesiologists, surgeons, and neuroscientists interested in optimizing patient safety during prolonged surgical procedures in non-supine positions.