Marc Zeffren
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About
Marc Zeffren is a clinician-researcher whose work centers on the diagnosis and management of rare neuroendocrine tumors, with a particular focus on secondary hypertension. His most-cited study, “Renal Paraganglioma: A Rare Case of Secondary Hypertension in a Young Patient” (2025), documents a 19-year-old woman who presented with acute abdominal pain and was found to have an incidental renal mass—ultimately identified as a catecholamine-secreting paraganglioma. This case highlights the critical importance of considering paragangliomas in young patients with unexplained hypertension, a clinical scenario that is frequently overlooked. By detailing the diagnostic pathway and surgical management, Zeffren provides a valuable educational resource for clinicians encountering similar presentations. Though early in his career, his work has already garnered attention for its clarity and clinical relevance. Zeffren’s contributions underscore the intersection of endocrinology, oncology, and nephrology, and his case report serves as a key reference for trainees and specialists alike who seek to recognize and treat these rare but curable causes of secondary hypertension.
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