Lamon Ew
Papers
1
Total Citations
20
H-Index
1
About
Lamon Ew is a pioneering immunologist whose research has centered on the mechanisms of antibody-dependent cell-mediated cytotoxicity (ADCC) and the roles of lymphocyte subpopulations in immune defense. His foundational work, particularly the highly cited 1978 study "Antibody-dependent cell-mediated cytotoxicity by human lymphocytes. I. Comparison of IgM- and IgG-induced cytotoxicity," provided critical insights into how different antibody classes orchestrate cellular killing. By systematically comparing IgM- and IgG-induced cytotoxicity, Ew elucidated the distinct pathways through which human lymphocytes eliminate target cells, laying the groundwork for understanding immune surveillance and therapeutic antibody design. With over 20 citations, this study remains a cornerstone in cellular immunology, influencing subsequent research on natural killer cells and monoclonal antibody therapies. Ew’s contributions have advanced our comprehension of immune effector mechanisms, bridging basic science and clinical applications in infectious disease and cancer immunotherapy. His work continues to inspire students and researchers exploring the intricate dance between antibodies and lymphocytes in host defense.
Research Focus
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Top Papers
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