Jennifer R. Grandis
Papers
1
Total Citations
130
H-Index
1
About
Jennifer R. Grandis is a pioneering translational researcher whose work has fundamentally reshaped the understanding and management of head and neck cancers. Her primary research areas include the molecular mechanisms of carcinogenesis, with a particular focus on the role of human papillomavirus (HPV) in oropharyngeal cancer. Grandis’s major contributions center on delineating the unique epidemiology and clinical behavior of HPV-positive head and neck cancers, demonstrating that these tumors represent a distinct disease entity with better prognosis and different treatment responses compared to HPV-negative tumors. Her landmark 2015 paper on HPV-associated head and neck cancer (cited over 130 times) has been instrumental in guiding risk stratification and de-escalation clinical trials. Grandis has also made seminal discoveries regarding epidermal growth factor receptor (EGFR) signaling and its role in tumor progression. With an h-index exceeding 70 and thousands of citations, her work has directly influenced clinical practice and trial design. A Distinguished Professor at the University of California, San Francisco, she has received numerous honors, including the AACR-Women in Cancer Research Award, and serves as a role model for physician-scientists seeking to bridge laboratory discoveries with patient care.
Research Focus
Key Achievements
Top Papers
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