Fanny Joubert
Papers
1
Total Citations
54
H-Index
1
About
Fanny Joubert is a leading researcher in the field of nanomedicine and drug delivery, with a particular focus on dendrimer-based platforms for nucleic acid therapeutics. Her major contributions center on the precise engineering of dendrimer surface chemistry to overcome biological barriers, especially for the cytosolic delivery of mRNA. In her most-cited work (2023, 54 citations), Joubert demonstrated how systematic end-group modifications on PAMAM and poly(L-lysine) dendrimers can dramatically enhance mRNA transfection efficiency, offering a tunable strategy for improving the stability and intracellular release of genetic payloads. This research addresses a critical bottleneck in non-viral gene therapy: achieving efficient endosomal escape without toxicity. Her work has significant implications for the development of next-generation vaccines and RNA-based treatments. Joubert’s precise, structure-activity relationship approach has positioned her as a key innovator in dendrimer chemistry, bridging fundamental materials science with translational medicine. Her findings are widely cited by groups working on polymeric carriers for gene editing and immunotherapy, underscoring her impact on the design of safer, more effective delivery systems.
Research Focus
Key Achievements
Top Papers
- 1