Papers
23
Total Citations
683
H-Index
12
About
Esther Wit is a pioneering surgical researcher whose work sits at the intersection of robotic surgery, radioguided techniques, and lymph node staging in prostate cancer. Her research has fundamentally advanced how surgeons detect and remove sentinel lymph nodes during robot-assisted radical prostatectomy, addressing one of the field's most persistent technical challenges: the limited maneuverability of conventional laparoscopic instruments in robotic settings. Wit's most influential contribution is her central role in developing and clinically translating the DROP-IN gamma probe, a tethered device that dramatically improves rotational freedom during robotic radioguided surgery. Her 2014 optimization of fluorescence guidance (119 citations) laid the groundwork for this trajectory, while her landmark 2018 first-in-human translation (82 citations) and subsequent 2020 clinical validation (90 citations) demonstrated the probe's real-world feasibility and safety. Beyond instrumentation, she has explored multimodal imaging strategies — combining fluorescence guidance, PSMA PET/CT, and sentinel node biopsy — to refine lymph node staging accuracy and reduce unnecessary dissection. Her multispectral fluorescence work further enables surgeons to distinguish prostate-draining from lower-limb lymphatics intraoperatively. Collectively accumulating over 580 citations, Wit's research represents a defining body of work shaping the future of image-guided, robot-assisted oncologic surgery.
Research Focus
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