David Steel

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About

David Steel is a leading ophthalmology researcher whose work focuses on optimizing surgical techniques for retinal therapies, particularly through biomechanical analysis. His major contributions center on refining subretinal injection protocols—a critical delivery method for emerging gene and cell therapies. In his highly cited 2024 paper, "Biomechanical considerations for optimising subretinal injections" (17 citations), Steel systematically investigates injection point selection and delivery parameters to precisely target specific retinal locations while minimizing tissue trauma. This work addresses a key translational challenge: improving the safety and efficacy of subretinal delivery, which is essential for treating inherited retinal diseases and macular degeneration. By integrating engineering principles with clinical ophthalmology, Steel provides evidence-based guidelines that help surgeons standardize procedures, reduce variability, and enhance therapeutic outcomes. His research bridges the gap between biomechanical modeling and practical surgical decision-making, making him a pivotal figure in advancing precision ocular drug delivery. Steel’s contributions are shaping how next-generation retinal therapies are administered, directly impacting the success of clinical trials and future treatments for blinding conditions.