Cosimo Mazzotta
Papers
1
Total Citations
136
H-Index
1
About
Dr. Cosimo Mazzotta is a leading ophthalmologist and researcher whose work has fundamentally advanced the field of corneal crosslinking (CXL) for keratoconus. His primary research focuses on optimizing CXL protocols, particularly through the development and clinical validation of accelerated and pulsed-light techniques. His landmark 2014 study, "Pulsed Light Accelerated Crosslinking versus Continuous Light Accelerated Crosslinking: One-Year Results," with 136 citations, is a seminal comparative analysis that demonstrated the superior efficacy and safety of pulsed-light accelerated CXL (pl-ACXL) over continuous-light methods. This work established a new standard for treatment, showing that pulsed delivery of high-fluence ultraviolet A irradiation, combined with dextran-free riboflavin, reduces stromal oxygen depletion and enhances biomechanical stiffening. Dr. Mazzotta’s contributions have directly improved patient outcomes by minimizing treatment time while maximizing corneal stability. His research is widely cited, reflecting its profound impact on clinical practice, and he is recognized globally as a pioneer in refining CXL protocols, making him a key figure in the fight against progressive keratoconus.
Research Focus
Key Achievements
Top Papers
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