Chaewon Lee
Papers
1
Total Citations
16
H-Index
1
About
Chaewon Lee is a translational pain researcher whose work bridges molecular pharmacology and clinical analgesia, with a focus on postoperative pain management. Her most cited study investigates VVZ-149, a novel dual-action analgesic that inhibits both the glycine transporter type 2 and the serotonin 5-HT2A receptor. In a randomized, double-blind, proof-of-concept trial involving patients undergoing laparoscopic and robotic-laparoscopic gastrectomy, Lee demonstrated that VVZ-149 significantly reduces the affective—or emotional—component of pain, a dimension often undertreated by conventional opioids. This work, cited 16 times, highlights her contribution to developing non-opioid alternatives that target both sensory and affective pain pathways. Lee’s research is notable for its direct clinical translation, addressing a critical need in perioperative care by offering a potential solution to opioid-related side effects and dependence. Her findings have implications for enhanced recovery after surgery (ERAS) protocols, positioning her as an emerging voice in mechanism-based pain therapeutics. For students and researchers, Lee’s work exemplifies how preclinical insights into neurotransmitter systems can be rigorously tested in human trials to reshape postoperative pain management.
Research Focus
Key Achievements
Top Papers
- 1