Brendan Geraghty

Papers

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About

Brendan Geraghty is a rising leader in ophthalmic biomechanics, with a research focus that bridges mechanical engineering and retinal therapeutics. His work centers on optimizing subretinal injection—a critical delivery method for emerging gene and cell therapies—by systematically defining the biomechanical parameters that govern injection success. In his landmark 2024 paper, "Biomechanical considerations for optimising subretinal injections," which has already garnered 17 citations, Geraghty provides the first rigorous framework for selecting injection points and delivery parameters to precisely target specified retinal locations. This contribution directly addresses a major clinical challenge: improving the accuracy and safety of subretinal delivery, which is essential for translating novel therapies from bench to bedside. His research has immediate implications for surgical planning and device design, offering quantitative guidelines that can reduce retinal damage and enhance therapeutic efficacy. By merging computational modeling with experimental validation, Geraghty is shaping the next generation of ophthalmic interventions, making him a key figure to watch in the field of ocular biomechanics and drug delivery.