Andrej Coer

Papers

Total Citations

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About

Andrej Coer’s research focuses on the molecular and cellular mechanisms underlying orthopedic implant failure, particularly septic loosening and periprosthetic joint infections. His most-cited work, “Human beta-defensin-3 producing cells in septic implant loosening” (2015), identifies beta-defensin-3 as a key antimicrobial peptide produced by immune cells in response to bacterial colonization around implants. This finding illuminates how the host immune system attempts to combat biofilm-associated infections, offering potential targets for diagnostic or therapeutic strategies. Coer’s contributions bridge immunology and orthopedics, providing insights into the local inflammatory environment that drives implant failure. With 9 citations, this paper has informed subsequent studies on antimicrobial peptides in musculoskeletal infections. His work is notable for its clinical relevance, directly addressing a major challenge in joint replacement surgery. Coer’s research continues to advance understanding of host-pathogen interactions at the bone-implant interface, aiming to improve outcomes for patients with prosthetic joints.