Amrei Windelberg
Papers
1
Total Citations
153
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1
About
Dr. Amrei Windelberg is a distinguished analytical biochemist whose pioneering work in metabolic diagnostics has profoundly impacted clinical understanding of vitamin deficiencies. Her primary research focuses on the development and validation of advanced mass spectrometry methods for quantifying biomarkers of cobalamin (vitamin B12) and folate status. Dr. Windelberg’s landmark contribution is the creation of a fully automated, isotope-dilution gas chromatography-mass spectrometry (GC-MS) assay that simultaneously measures methylmalonic acid (MMA), total homocysteine (tHcy), and related amino acids in human serum or plasma. This single, high-throughput method revolutionized clinical diagnostics by enabling the precise differentiation between B12 and folate deficiencies—a critical distinction for effective patient treatment. Her seminal 2005 paper describing this technique has garnered over 150 citations, reflecting its enduring value as a gold-standard reference in the field. By streamlining complex metabolic profiling into a robust, automated protocol, Dr. Windelberg’s work has empowered clinicians and researchers worldwide to conduct more accurate, efficient assessments of nutritional status, directly improving patient care and advancing our understanding of one-carbon metabolism.
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Top Papers
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