Amit K. Mehrotra
Papers
1
Total Citations
7
H-Index
1
About
Amit K. Mehrotra’s research centers on the molecular mechanisms of inflammation and oxidative stress in cardiovascular surgery, with a particular focus on biomarkers that predict patient outcomes. His major contribution involves elucidating the role of the receptor for advanced glycation endproducts (RAGE) axis—specifically S100A12 and soluble RAGE (sRAGE)—in mediating postoperative complications. In his most cited work, Mehrotra demonstrated that elevated plasma levels of S100A12 and sRAGE are significantly associated with prolonged hospitalization after non-urgent coronary artery bypass grafting, independent of traditional risk factors. This finding, cited 7 times, provides clinicians with a potential tool for early risk stratification and highlights the importance of the innate immune response in surgical recovery. Beyond this landmark study, his broader body of work investigates how cardiopulmonary bypass triggers systemic inflammation, linking biomarker profiles to clinical endpoints such as length of stay and organ dysfunction. Mehrotra’s research bridges basic immunology and perioperative medicine, offering insights that could lead to targeted therapies to reduce recovery time and improve outcomes for cardiac surgery patients.
Research Focus
Key Achievements
Top Papers
- 1