Correlation analysis between 2D and quasi-3D gamma evaluations for both intensity-modulated radiation therapy and volumetric modulated arc therapy

Abstract

// Jung-in Kim 1,2,3 , Chang Heon Choi 1,2,3,4 , Hong-Gyun Wu 1,2,3,5 , Jin Ho Kim 1,2,3 , Kyubo Kim 6 and Jong Min Park 1,2,3,4 1 Department of Radiation Oncology, Seoul National University Hospital, Seoul, Republic of Korea 2 Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea 3 Biomedical Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea 4 Center for Convergence Research on Robotics, Advanced Institutes of Convergence Technology, Suwon, Republic of Korea 5 Department of Radiation Oncology, Seoul National University College of Medicine, Seoul, Republic of Korea 6 Department of Radiation Oncology, Ewha Womans University School of Medicine, Seoul, Republic of Korea Correspondence to: Jong Min Park, email: // Keywords : 2D gamma evaluation, quasi-3D gamma evaluation, pre-treatment patient-specific quality assurance, intensity-modulated radiation therapy, volumetric modulated arc therapy Received : July 04, 2016 Accepted : September 21, 2016 Published : September 27, 2016 Abstract The aim of this work was to investigate correlations between 2D and quasi-3D gamma passing rates. A total of 20 patients (10 prostate cases and 10 head and neck cases, H&N) were retrospectively selected. For each patient, both intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) plans were generated. For each plan, 2D gamma evaluation with radiochromic films and quasi-3D gamma evaluation with fluence measurements were performed with both 2%/2 mm and 3%/3 mm criteria. Gamma passing rates were grouped together according to delivery techniques and treatment sites. Statistical analyses were performed to examine the correlation between 2D and quasi-3D gamma evaluations. Statistically significant difference was observed between delivery techniques only in the quasi-3D gamma passing rates with 2%/2 mm. Statistically significant differences were observed between treatment sites in the 2D gamma passing rates (differences of less than 8%). No statistically significant correlations were observed between 2D and quasi-3D gamma passing rates except the VMAT group and the group including both IMRT and VMAT with 3%/3 mm ( r = 0.564 with p = 0.012 for theVMAT group and r = 0.372 with p = 0.020 for the group including both IMRT and VMAT), however, those were not strong. No strong correlations were observed between 2D and quasi-3D gamma evaluations.