Signal transduction

Hedgehog Target Genes: Mechanisms of Carcinogenesis Induced by Aberrant Hedgehog Signaling Activation

Yuriko Katoh, Masaru Katoh

引用数: 520 • 2009

R2‐P2 rapid‐robotic phosphoproteomics enables multidimensional cell signaling studies

Mario Leutert, Ricard A. Rodríguez‐Mias, Noelle K. Fukuda, Judit Villén

引用数: 204 • 2019

An efficient rapid system for profiling the cellular activities of molecular libraries

Jonathan S. Melnick, Jeff Janes, Sung Joon Kim, Jim Chang, Daniel G. Sipes, Drew Gunderson, Laura Jarnes, Jason Matzen, Michael Garcia, Tami Hood, Ronak Beigi, Gang Xia, Richard A. Harig, Hayk Asatryan, S. Frank Yan, Yingyao Zhou, Xiang-ju Gu, Alham Saadat, Vicki Zhou, Frederick J. King, Christopher M. Shaw, Andrew I. Su, Robert T. Downs, Nathanael S. Gray, Peter G. Schultz, Markus Warmuth, Jeremy S. Caldwell

引用数: 185 • 2006

c-Src protein kinase inhibitors block assembly and maturation of dengue virus

Justin Jang Hann Chu, Priscilla L. Yang

引用数: 137 • 2007

Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models.

Ting-Xin Jiang, Randall B. Widelitz, Wei-Min Shen, Peter Will, Da-Yu Wu, Chih‐Min Lin, Han-Sung Jung, Cheng‐Ming Chuong

引用数: 129 • 2004

Logic‐Gate‐Actuated DNA‐Controlled Receptor Assembly for the Programmable Modulation of Cellular Signal Transduction

Shan Chen, Zhifei Xu, Wen Yang, Xiahui Lin, Jingying Li, Huanghao Yang

引用数: 124 • 2019

Pro-apoptotic Proteins Released from the Mitochondria Regulate the Protein Composition and Caspase-processing Activity of the Native Apaf-1/Caspase-9 Apoptosome Complex

Davina Twiddy, David G. Brown, Colin Adrain, Rebekah Jukes, Séamus J. Martin, Gerald M. Cohen, Marion MacFarlane, Kelvin Cain

引用数: 120 • 2004

A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer

Erdem Bangi, Celina Ang, Peter Smibert, Andrew Uzilov, Alexander Teague, Yevgeniy Antipin, Rong Chen, Chana Hecht, Nelson Gruszczynski, Wesley J. Yon, Denis Malyshev, Denise Laspina, Isaiah Selkridge, Aye S. Moe, Chun Yee Lau, Patricia Taik, Eric Wilck, Aarti Sonia Bhardwaj, Max W. Sung, Sara Kim, Kendra Yum, Robert Sebra, Michael Donovan, Krzysztof Misiukiewicz, Eric E. Schadt, Marshall R. Posner, Ross Cagan

引用数: 107 • 2019

First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass

Guangliang Wang, Surendra K. Rajpurohit, Fabien Delaspre, Steven L. Walker, David T. White, Alexis M. Ceasrine, Rejji Kuruvilla, Ruo‐Jing Li, Joong Sup Shim, Jun O. Liu, Michael Parsons, Jeff S. Mumm

引用数: 100 • 2015

Identification of a Novel Inhibitory Actin-capping Protein Binding Motif in CD2-associated Protein

Serawit Bruck, Tobias B. Huber, Robert J. Ingham, Kyoungtae Kim, Hanspeter Niederstrasser, Paul M. Allen, Tony Pawson, John A. Cooper, Andréy S. Shaw

引用数: 93 • 2006

Tumor Cell Pseudopodial Protrusions

Zongjian Jia, Laurence Barbier, Heather Stuart, Mohammad Amraei, Steven Pelech, James W. Dennis, Pavel Metalnikov, Paul O’Donnell, Ivan R. Nabi

引用数: 76 • 2005

A Homogeneous Fluorescence Polarization Assay Adaptable for a Range of Protein Serine/Threonine and Tyrosine Kinases

Elizabeth A. Gaudet, Kuo‐Sen Huang, Yan Zhang, Wei Huang, David Mark, J. Richard Sportsman

引用数: 74 • 2003

Manipulation of EphB2 Regulatory Motifs and SH2 Binding Sites Switches MAPK Signaling and Biological Activity

Jiefei Tong, Sabine Elowe, Piers Nash, Tony Pawson

引用数: 70 • 2003

Novel Src Homology 3 Domain-binding Motifs Identified from Proteomic Screen of a Pro-rich Region

Christina Y. H. Jia, Jing Nie, Chenggang Wu, Chengjun Li, Shawn S.‐C. Li

引用数: 65 • 2005

Targeting N-myristoylation for therapy of B-cell lymphomas

Erwan Beauchamp, Megan C. Yap, Aishwarya Iyer, Maneka A. Perinpanayagam, Jay M. Gamma, Krista M. Vincent, Manikandan Lakshmanan, Anandhkumar Raju, Vinay Tergaonkar, Soo‐Yong Tan, Soon Thye Lim, Weifeng Dong, Lynne‐Marie Postovit, Kevin D. Read, David W. Gray, Paul G. Wyatt, John R. Mackey, Luc G. Berthiaume

引用数: 64 • 2020

Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain

Axel Visel, Gonzalo Álvarez-Bolado, Christina Thaller, Gregor Eichele

引用数: 62 • 2006

A Solid-Phase Assay for the Determination of Protein Tyrosine Kinase Activity of c-src Using Scintillating Microtitration Plates

Albert Braunwalder, Donna Yarwood, Tony Hall, Martin Missbach, Kenneth E. Lipson, Matthew A. Sills

引用数: 59 • 1996

Cell membrane array fabrication and assay technology

Victoria Yamazaki, Oksana Sirenko, Robert J. Schafer, Luat Nguyen, Thomas Gutsmann, Lore Brade, Jay T. Groves

引用数: 53 • 2005

Merlin Links to the cAMP Neuronal Signaling Pathway by Anchoring the RIβ Subunit of Protein Kinase A

Mikaela Grönholm, Lutz Vossebein, Cathrine R. Carlson, Juha Kuja‐Panula, Tambet Teesalu, Kaija Alfthan, Antti Vaheri, Heikki Rauvala, Friedrich W. Herberg, Kjetil Taskén, Olli Carpén

引用数: 52 • 2003

Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach

Wei Chen, Minyong Chen, Larry S. Barak

引用数: 51 • 2010