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Stereodivergent synthesis with a programmable molecular machine

Salma Kassem, Alan T. L. Lee, David A. Leigh, Vanesa Marcos, Leoni I. Palmer, Simone Pisano

引用数: 177 • 2017

Exploration of Enzyme Diversity by Integrating Bioinformatics with Expression Analysis and Biochemical Characterization

Pavel Vaňáček, Eva Šebestová, Petra Bábková, Šárka Bidmanová, Lukáš Daniel, Pavel Dvořák, Veronika Štěpánková, Radka Chaloupková, Jan Brezovský, Zbyněk Prokop, Jiřı́ Damborský

引用数: 93 • 2018

Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site‐Saturated Libraries

Martyn Hulley, Helen S. Toogood, Anna Fryszkowska, David Mansell, Gill Stephens, John M. Gardiner, Nigel S. Scrutton

引用数: 58 • 2010

Identification of Small-Molecule Inhibitors of Nucleoside Triphosphate Hydrolase in <i>Toxoplasma gondii</i>

Takashi Asai, Tsutomu Takeuchi, Jeff Diffenderfer, L. David Sibley

引用数: 44 • 2002

Crystal Structure of a Nicotinate Phosphoribosyltransferase from Thermoplasma acidophilum

Dong Hae Shin, Natalia Oganesyan, Jaru Jancarik, Hisao Yokota, Rosalind Kim, Sung‐Hou Kim

引用数: 38 • 2005

Interaction of Mycobacterium tuberculosis CYP130 with Heterocyclic Arylamines

Larissa M. Podust, Hugues Ouellet, Jens Peter von Kries, Paul R. Ortiz de Montellano

引用数: 37 • 2009

Crystal Structure of Bacillus anthracis Transpeptidase Enzyme CapD

Ruiying Wu, Stefan Richter, Rongguang Zhang, Valerie J. Anderson, Dominique Missiakas, A. Joachimiak

引用数: 33 • 2009

Diffusion-controlled enzyme-catalyzed molecular communication system for targeted drug delivery

Uche A. K. Chude-Okonkwo

引用数: 27 • 2014

Structural Evidence of a Passive Base-flipping Mechanism for β-Glucosyltransferase

Laurent Larivière, S. Moréra

引用数: 21 • 2004

Efficient screening for new amino acid dehydrogenase activity: Directed evolution of Bacillus sphaericus phenylalanine dehydrogenase towards activity with an unsaturated non-natural amino acid

Sihong Chen, Paul C. Engel

引用数: 19 • 2009

Crystal structure of γ‐glutamyl phosphate reductase (TM0293) from <i>Thermotoga maritima</i> at 2.0 Å resolution

Rebecca Page, Michael S. Nelson, F. von Delft, Marc‐André Elsliger, Jaume M. Cánaves, Linda S. Brinen, Xiaoping Dai, Ashley M. Deacon, Ross Floyd, Adam Godzik, Carina Grittini, Slawomir K. Grzechnik, Lukasz Jaroszewski, Heath E. Klock, Eric Koesema, John S. Kovarik, Andreas Kreusch, Peter Kühn, Scott A. Lesley, Daniel McMullan, Timothy McPhillips, Mitchell D. Miller, Andrew T. Morse, Kin Moy, Jie Ouyang, Alyssa Robb, Kevin Rodrigues, Robert Schwarzenbacher, Glen Spraggon, Raymond C. Stevens, Henry van den Bedem, Jeff Velasquez, Juli Vincent, Xianhong Wang, Bill West, Guenter Wolf, Keith O. Hodgson, John Wooley, Ian A. Wilson

引用数: 18 • 2003

Nanomechanical constraints acting on the catalytic site of cellular RNA polymerases

Robert O. J. Weinzierl

引用数: 11 • 2010

Putative implication of α‐amylase loop 7 in the mechanism of substrate binding and reaction products release

G. André, V.H. Tran

引用数: 9 • 2004

Crystal structure of a PduO‐type ATP:cobalamin adenosyltransferase from <i>Burkholderia thailandensis</i>

Jin Ho Moon, Ae Kyung Park, Eun Hyuk Jang, Sun Kim, Young Sil Min

引用数: 5 • 2008