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Site-to-site peptide transport on a molecular platform using a small-molecule robotic arm

Salma Kassem, Alan T. L. Lee, David A. Leigh, Augustinas Markevicius, Daniel J. Tetlow, Naoyuki Toriumi

发表年份
2020
引用次数
14
访问权限
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摘要

H NMR. The size of the peptide cargo has no significant effect on the rate or efficiency of transport in either direction. The new operating conditions allow detailed physical organic chemistry of the ratcheted transport mechanism to be uncovered, improve efficiency, and enable the transport of more complex cargoes than was previously possible.

关键词

IsomerizationProtonationMolecular switchChemistryDeprotonationYield (engineering)MoleculeSolventSubstrate (aquarium)Dynamic covalent chemistry

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