Synthetic biology

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

Jeremy J. Agresti, Eugene Antipov, Adam R. Abate, Keunho Ahn, Amy C. Rowat, Jean‐Christophe Baret, Manuel Márquez, Alexander M. Klibanov, Andrew D. Griffiths, David A. Weitz

Citations: 1147 • 2010

Universal computing by DNA origami robots in a living animal

Yaniv Amir, Eldad Ben-Ishay, Daniel Levner, Shmulik Ittah, Almogit Abu-Horowitz, Ido Bachelet

Citations: 374 • 2014

Strategies to maximize heterologous protein expression in Escherichia coli with minimal cost

Wolfgang Peti, Rebecca Page

Citations: 227 • 2006

Automated multiplex genome-scale engineering in yeast

Tong Si, Ran Chao, Yuhao Min, Yuying Wu, Wen Ren, Huimin Zhao

Citations: 201 • 2017

A cellular platform for the development of synthetic living machines

Douglas Blackiston, Emma K. Lederer, Sam Kriegman, Simon Garnier, Joshua Bongard, Michael Levin

Citations: 182 • 2021

An artificial intelligence enabled chemical synthesis robot for exploration and optimization of nanomaterials

Yibin Jiang, Daniel Salley, Abhishek Sharma, Graham Keenan, Margaret Mullin, Leroy Cronin

Citations: 179 • 2022

Robotic DNA Nanostructures

Sami Nummelin, Boxuan Shen, Petteri Piskunen, Qing Liu, Mauri A. Kostiainen, Veikko Linko

Citations: 167 • 2020

Droplet microfluidics for synthetic biology

Philip C. Gach, Kosuke Iwai, Peter W. Kim, Nathan J. Hillson, Anup K. Singh

Citations: 130 • 2017

Logic‐Gate‐Actuated DNA‐Controlled Receptor Assembly for the Programmable Modulation of Cellular Signal Transduction

Shan Chen, Zhifei Xu, Wen Yang, Xiahui Lin, Jingying Li, Huanghao Yang

Citations: 124 • 2019

Engineered communications for microbial robotics

Ron Weiss, Thomas F. Knight

Citations: 112 • 2001

Advances in directed protein evolution by recursive genetic recombination: applications to therapeutic proteins

Aaron L. Kurtzman, Sridhar Govindarajan, Katherine Vahle, Jennifer T. Jones, Volker Heinrichs, Phillip A. Patten

Citations: 111 • 2001

High-fidelity gene synthesis by retrieval of sequence-verified DNA identified using high-throughput pyrosequencing

Mark Matzas, Peer F. Stähler, Nathalie Kefer, Nicole Siebelt, Valesca Boisguérin, Jack T. Leonard, Andreas Keller, Cord Stähler, Pamela Häberle, Baback Gharizadeh, Farbod Babrzadeh, George M. Church

Citations: 98 • 2010

An End-to-End Workflow for Engineering of Biological Networks from High-Level Specifications

Jacob Beal, Ron Weiss, Douglas Densmore, Aaron Adler, Evan Appleton, Jonathan Babb, Swapnil Bhatia, Noah Davidsohn, Traci L. Haddock, Joseph Loyall, Richard Schantz, Viktor Vasilev, Fusun Yaman

Citations: 89 • 2012

Synthetic biology meets bioprinting: enabling technologies for humans on Mars (and Earth)

Lynn J. Rothschild

Citations: 82 • 2016

Controlling cell-free metabolism through physiochemical perturbations

Ashty S. Karim, Jacob T. Heggestad, Samantha A. Crowe, Michael C. Jewett

Citations: 82 • 2017

Principles of synthetic biology

Citations: 77 • 2021

Accelerating strain engineering in biofuel research via build and test automation of synthetic biology

Jianzhi Zhang, Yongcan Chen, Lihao Fu, Erpeng Guo, Bo Wang, Lei Dai, Tong Si

Citations: 68 • 2021

Enabling high‐throughput biology with flexible open‐source automation

Emma J. Chory, Dana Gretton, Erika A. DeBenedictis, Kevin M. Esvelt

Citations: 68 • 2021

Synthetic morphology with agential materials

Jamie A. Davies, Michael Levin

Citations: 66 • 2023

Protein engineering via Bayesian optimization-guided evolutionary algorithm and robotic experiments

Ruyun Hu, Lihao Fu, Yongcan Chen, Junyu Chen, Yu Qiao, Tong Si

Citations: 60 • 2022