Zach Hamilton

Papers

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About

Dr. Zach Hamilton is a leading urologic oncologist whose research focuses on optimizing surgical outcomes for patients undergoing radical cystectomy, the standard treatment for muscle-invasive bladder cancer. His most cited work, "Alvimopan in an Enhanced Recovery Program Following Radical Cystectomy" (2015, 19 citations), demonstrates his commitment to perioperative care innovation. In this pivotal study, Dr. Hamilton investigated the use of alvimopan—an FDA-approved peripherally acting μ-opioid receptor antagonist—within an enhanced recovery after surgery (ERAS) protocol. His findings showed that alvimopan significantly accelerates gastrointestinal recovery and reduces postoperative ileus, a common and debilitating complication, ultimately shortening hospital stays. This contribution has helped shape modern ERAS protocols in urologic oncology, directly improving patient quality of life and reducing healthcare costs. Dr. Hamilton’s work bridges the gap between pharmaceutical advances and practical surgical care, establishing him as a key figure in evidence-based perioperative management. His research continues to influence clinical guidelines and inspire further studies on multimodal recovery strategies for major oncologic surgeries.