Papers
1
Total Citations
59
H-Index
1
About
Yves Ambroise is a biochemist and molecular endocrinologist whose research centers on the sodium iodide symporter (NIS), a critical membrane protein that mediates active iodide transport in the thyroid and other tissues. His most notable contribution is the development of a nonradioactive iodide uptake assay for assessing NIS function, published in 2009 and cited 59 times. This innovative method replaced traditional radioactive iodine assays, enabling safer, more accessible, and high-throughput screening of NIS activity—a breakthrough for studying thyroid physiology, iodide transport disorders, and the effects of environmental disruptors or therapeutic compounds. Ambroise’s work has directly advanced the understanding of NIS regulation in health and disease, including its role in thyroid cancer and radioiodine therapy. By providing a practical tool for laboratories worldwide, his assay has become a standard technique in the field, facilitating research on iodide metabolism and the development of NIS-targeted drugs. His contributions underscore a commitment to bridging molecular biology with translational applications, making him a respected figure in thyroid research and membrane transport biology.
Research Focus
Key Achievements
Top Papers
- 1A nonradioactive iodide uptake assay for sodium iodide symporter function59 citations · 2009