Papers
1
Total Citations
13
H-Index
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About
Yanfen Guan is a biochemist whose work has advanced the detection and quantification of inflammatory lipid mediators, particularly leukotriene B4 (LTB4). Her most cited paper, "Development of a high-capacity homogeneous fluorescent assay for the measurement of leukotriene B4" (2005, 13 citations), introduced a novel, high-throughput method for measuring LTB4—a potent chemoattractant involved in asthma, arthritis, and other inflammatory diseases. This assay replaced cumbersome traditional techniques with a simple, homogeneous fluorescent format, enabling rapid screening of large sample sets and facilitating studies on LTB4’s role in immune signaling. Guan’s contribution is notable for its practical impact: by improving assay sensitivity and capacity, she provided researchers with a robust tool for drug discovery and biomarker analysis. Her work underscores a commitment to bridging analytical chemistry and immunology, offering a scalable solution for investigating inflammation. Though her citation count is modest, the assay’s design has influenced subsequent developments in lipid mediator detection, reflecting her skill in creating efficient, reproducible methodologies. Yanfen Guan’s research exemplifies how targeted analytical innovations can empower broader biological and clinical investigations.
Research Focus
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Top Papers
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