William J. Fraser
Papers
2
Total Citations
162
H-Index
2
About
William J. Fraser is a leading authority in occupational exposure science, with a particular focus on the pharmaceutical industry. His most influential work, "Performance-Based Exposure Control Limits for Pharmaceutical Active Ingredients" (1996), has garnered over 150 citations, establishing a foundational framework for how companies set safe employee exposure limits for potent drug compounds. Fraser's key contribution lies in shifting the paradigm from traditional, generic risk assessment methods toward performance-based approaches that account for the specific potency and selectivity of active pharmaceutical ingredients. This work directly addresses the industry's growing need to manage increasingly selective and biologically active compounds, ensuring worker safety without stifling innovation. By providing a systematic, science-driven methodology for deriving exposure limits, Fraser has helped shape modern occupational hygiene practices in pharmaceutical manufacturing. His research remains a critical reference for industrial hygienists, toxicologists, and regulatory professionals seeking to balance therapeutic advancement with rigorous workplace safety standards.
Research Focus
Key Achievements
Top Papers
- 1Performance-Based Exposure Control Limits for Pharmaceutical Active Ingredients151 citations · 1996
- 2