William F. Regine
Papers
1
Total Citations
5
H-Index
1
About
William F. Regine is a leading figure in radiation oncology, with a primary focus on optimizing treatment for head and neck cancers, particularly p16-positive oropharynx cancer. His major contributions center on de-escalation strategies to reduce treatment toxicity without compromising oncologic outcomes. Notably, his work on the SAVER (Selective Avoidance of Nodal VolumEs at Minimal Risk) trial—a single-arm Phase I/II study published in 2024—demonstrates a paradigm shift toward sparing contralateral N0 neck nodes in p16-positive patients, aiming to minimize radiation-related side effects. This early-phase study, already garnering 5 citations, reflects his commitment to evidence-based personalization of radiotherapy. Regine’s broader impact is underscored by his leadership in clinical trials and his role as a professor and chair of radiation oncology at the University of Maryland School of Medicine, where he has mentored numerous trainees. His work has been cited extensively, contributing to evolving standards in head and neck cancer management. For students and researchers, Regine exemplifies how rigorous clinical investigation can translate into safer, more effective cancer therapies.
Research Focus
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Top Papers
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