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About

Uwe A. Wittel is a leading surgical oncologist whose research focuses on advancing minimally invasive techniques for pancreatic surgery, particularly for cancer. His major contributions center on rigorously comparing the safety, oncological adequacy, and short-term outcomes of minimally invasive approaches—including laparoscopic and robot-assisted procedures—against traditional open surgery. His landmark DIPLOMA study (2017, 280 citations) provided crucial evidence that minimally invasive distal pancreatectomy can achieve comparable oncological outcomes to open surgery for pancreatic ductal adenocarcinoma. Wittel also co-developed the updated Alternative Fistula Risk Score (ua-FRS, 2019, 195 citations), a vital tool for predicting postoperative pancreatic fistula after minimally invasive pancreatoduodenectomy. Through large, pan-European, propensity-matched studies (2018, 159 citations; 2020), he has systematically demonstrated the benefits and limitations of these advanced techniques. His recent work extends to comparing robot-assisted versus laparoscopic pancreatoduodenectomy (2024) and evaluating extended left pancreatectomy (2025). With over 690 citations across his most influential papers, Wittel’s research directly shapes clinical guidelines and surgical decision-making, making him a pivotal figure in the global shift toward safer, minimally invasive pancreatic surgery.