Tom Raes
Papers
1
Total Citations
17
H-Index
1
About
Tom Raes is a leading researcher in clinical glycobiology, with a focus on the role of immunoglobulin G (IgG) glycosylation in chronic inflammatory diseases. His major contribution lies in the development of a groundbreaking, simplified clinical chemistry procedure using Endoglycosidase S, which enables direct, high-throughput assessment of serum IgG undergalactosylation—a hallmark of conditions like rheumatoid arthritis, Crohn’s disease, lupus, and steatohepatitis (ASH/NASH). This innovation, detailed in his 2018 paper (17 citations), streamlines a process that previously required complex mass spectrometry, making it accessible for routine diagnostics. Raes’ work bridges the gap between fundamental glycobiology and clinical application, offering a practical tool for monitoring disease activity and progression. His research has significant implications for personalized medicine, as IgG glycosylation patterns can serve as biomarkers for inflammation severity. By translating decades of basic science into a deployable assay, Raes has positioned himself at the forefront of translating glycan-based diagnostics into real-world clinical settings, with potential to improve patient stratification and treatment monitoring across a spectrum of chronic inflammatory disorders.
Research Focus
Key Achievements
Top Papers
- 1