Thomas D. Pollard

Papers

Total Citations

393

H-Index

About

Thomas D. Pollard is a pioneering cell biologist whose research has fundamentally shaped our understanding of cytoskeletal dynamics and cell motility. His work centers on the molecular mechanisms of actin polymerization, particularly how cells control their shape and movement. Pollard's landmark contributions include the discovery and characterization of profilin, an actin-binding protein that regulates filament assembly, and the elucidation of the Arp2/3 complex's role in nucleating actin filaments. His 2000 paper on the dendritic nucleation model of actin polymerization remains a cornerstone of the field, with over 3,500 citations. With a total citation count exceeding 60,000, Pollard's impact is immense. He has also made significant advances in understanding cytokinesis, notably through his studies on the contractile ring in fission yeast. A member of the National Academy of Sciences and recipient of the Gairdner International Award, Pollard's work continues to inspire new generations of researchers exploring the intricate machinery of the cell.