Papers
5
Total Citations
77
H-Index
3
About
Dr. T. Charles is a leading urologic surgeon and researcher whose work centers on optimizing surgical outcomes for renal cell carcinoma, with a particular focus on minimally invasive, nephron-sparing techniques. Their major contributions lie in the rigorous, multi-institutional comparison of robotic-assisted partial nephrectomy (RPN) against traditional open surgery. A landmark study, the UroCCR-47 analysis, which has garnered 46 citations, demonstrated that RPN offers significant perioperative advantages without compromising oncological safety. Dr. Charles has further shaped clinical practice by investigating the prognostic impact of positive surgical margins after RAPN (MARGINS study) and by pioneering comparative effectiveness research in vulnerable populations, such as patients over 75 and those with obesity. Their work on the UroCCR-43 Robese study and the comparison of RPN to percutaneous ablation in elderly patients provides critical, evidence-based guidance for tailoring treatment. Through the prospective UROCCR Study 82, Dr. Charles has also advanced the understanding of how histological variants of RCC influence recurrence risk. By consistently leveraging large, national registries, Dr. Charles provides the high-level evidence needed to refine surgical decision-making and improve long-term outcomes for kidney cancer patients.
Research Focus
Key Achievements
Top Papers
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