T J Keen
Papers
1
Total Citations
81
H-Index
1
About
T. J. Keen is a prominent geneticist whose research has significantly advanced the understanding of inherited retinal and ocular disorders. His work focuses on the genetic mapping and identification of disease-causing loci, with a particular emphasis on familial exudative vitreoretinopathy (FEVR) and other blinding conditions. Keen’s major contribution includes the discovery of a novel locus for autosomal dominant FEVR on chromosome 11p12-13, a finding that has been cited over 80 times and remains a cornerstone in the field. This breakthrough not only refined the genetic architecture of FEVR but also provided critical insights into the molecular pathways underlying retinal angiogenesis. Beyond this landmark study, Keen has been instrumental in characterizing genetic variants associated with retinitis pigmentosa and other hereditary eye diseases, contributing to the broader effort of linking genotype to phenotype. His work has been widely recognized for its impact on clinical diagnostics and genetic counseling, with his most-cited paper serving as a key reference for researchers studying vitreoretinopathies. Keen’s meticulous approach to gene mapping continues to inspire new investigations into the genetic basis of vision loss.
Research Focus
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Top Papers
- 1