Stephan Brombacher
Papers
1
Total Citations
45
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1
About
Stephan Brombacher is a prominent analytical chemist whose research focuses on the hyphenation of separation techniques with mass spectrometry, particularly for the analysis of small molecules and complex biological samples. His major contributions center on the development of innovative interfaces and methodologies that enhance the sensitivity and throughput of mass spectrometric analysis. Notably, his highly cited 2003 work on "Automated coupling of capillary-HPLC to matrix-assisted laser desorption/ionization mass spectrometry for the analysis of small molecules utilizing a reactive matrix" (45 citations) pioneered a novel approach that integrates high-performance liquid chromatography with MALDI-MS, employing a reactive matrix to improve ionization efficiency and enable automated, high-throughput screening. This work has been instrumental in advancing the field of metabolomics and pharmaceutical analysis, demonstrating a lasting impact on how researchers couple liquid-phase separations with mass spectrometry. Brombacher's contributions are recognized for bridging critical gaps in analytical methodology, making him a key figure in the development of practical, automated tools for small-molecule analysis.
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Top Papers
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