Siyi Zou

Papers

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About

Dr. Siyi Zou is a surgical oncologist whose research focuses on prognostic biomarkers in pancreatic cancer, particularly the role of coagulation and fibrinolytic markers in predicting patient outcomes. Her most cited work, "Preoperative plasma D-dimer independently predicts survival in patients with pancreatic ductal adenocarcinoma undergoing radical resection" (2021, 8 citations), addresses a critical gap in the literature by demonstrating that elevated preoperative D-dimer levels serve as an independent predictor of poor survival in patients with pancreatic ductal adenocarcinoma after radical surgery. This finding challenges the controversy surrounding D-dimer's clinical significance in this context and provides surgeons with a readily available, low-cost tool for preoperative risk stratification. By systematically analyzing coagulation parameters in a large surgical cohort, Dr. Zou has contributed valuable evidence supporting the integration of D-dimer into prognostic models for pancreatic cancer. Her work underscores the importance of tumor-associated coagulopathy in cancer biology and offers practical implications for personalized surgical decision-making. Dr. Zou's research continues to advance the understanding of how routine laboratory markers can enhance prognostic accuracy in one of the most lethal malignancies.