Silke Tribius
Papers
1
Total Citations
13
H-Index
1
About
Silke Tribius is a leading clinical researcher in head and neck oncology, with a primary focus on optimizing treatment strategies for oropharyngeal squamous cell carcinoma (OPSCC). Her most significant contribution is the design and execution of the TopROC trial, a landmark comparative effectiveness study that directly compared transoral head and neck surgery with adjuvant radio(chemo)therapy against primary radiochemotherapy for loco-regionally advanced, transorally resectable OPSCC. This work, published in 2020, addresses a critical clinical equipoise, providing high-quality evidence to guide treatment decisions in a field where both surgical and non-surgical approaches are standard. With 13 citations, the TopROC trial has already shaped clinical discussions and trial design. Beyond this, Tribius’s research portfolio spans risk-adapted adjuvant therapy, the role of HPV status in treatment de-escalation, and functional outcomes. Her work is instrumental in moving the field toward more personalized, evidence-based care, balancing oncologic efficacy with quality of life. For students and researchers, Tribius exemplifies how rigorous comparative effectiveness research can directly impact clinical practice in head and neck cancer.
Research Focus
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Top Papers
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