Sean Lal
Papers
1
Total Citations
15
H-Index
1
About
Dr. Sean Lal is a cardiovascular researcher whose work focuses on the molecular mechanisms underlying acute coronary syndrome and heart failure. His key research areas include the role of microparticles—small membrane fragments released from cells—as inflammatory biomarkers in cardiovascular disease. In his notable 2008 study, Dr. Lal pioneered the use of antibody arrays to detect and characterize microparticles from acute coronary syndrome patients based on their cluster of differentiation (CD) antigen expression. This work, which has garnered 15 citations, provided a novel method for identifying circulating microparticles as potential markers of vascular inflammation and plaque instability. By demonstrating that these particles are elevated in patients with acute coronary syndrome, Dr. Lal contributed to a growing understanding of how cellular debris can signal disease activity. His research has implications for improving early diagnosis and risk stratification in cardiovascular medicine. Dr. Lal continues to investigate the pathological roles of microparticles and other inflammatory mediators, advancing knowledge of how molecular signatures can be harnessed for clinical benefit in heart disease.
Research Focus
Key Achievements
Top Papers
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