Sarah Hoang
Papers
1
Total Citations
47
H-Index
1
About
Sarah Hoang has made pivotal contributions to clinical genetics, particularly in advancing the detection of genome imbalances through array comparative genomic hybridisation (CGH). Her landmark 2010 paper, cited 47 times, demonstrated that array CGH could effectively replace traditional postnatal karyotyping as a first-line diagnostic test for genome-wide imbalances. This work provided critical validation and implementation strategies, showing that array CGH offers a substantially higher diagnostic yield than G-banded chromosome analysis. By systematically comparing the two methods, Hoang helped establish a new standard of care in cytogenetics, enabling more precise and comprehensive detection of chromosomal abnormalities. Her research has directly influenced clinical guidelines and laboratory practices, improving diagnostic accuracy for patients with developmental disorders and congenital anomalies. Beyond this seminal study, Hoang’s work continues to shape the integration of genomic technologies into routine diagnostics, underscoring her role as a key figure in the transition from conventional karyotyping to molecular cytogenetics. Her contributions have had lasting impact on how genetic imbalances are identified, benefiting countless patients and clinicians worldwide.
Research Focus
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