Sara Orlando
Papers
1
Total Citations
6
H-Index
1
About
Sara Orlando is a clinical physiologist and anesthesiology researcher whose work focuses on the intricate mechanics of mechanical ventilation during surgery, particularly in laparoscopic procedures. Her primary research areas include perioperative lung protection, positive end-expiratory pressure (PEEP) titration, and the pathophysiology of ventilator-induced lung injury. Orlando’s most notable contribution is the development and validation of the recruitment-to-inflation (R/I) ratio as a bedside tool to assess lung recruitability and individualize PEEP settings. Her landmark 2024 physiologic study, which has already garnered 6 citations, demonstrated how pneumoperitoneum-induced abdominal pressure alters lung mechanics and showed that the R/I ratio can effectively predict which patients will benefit from higher PEEP during laparoscopic surgery. This work provides a practical, evidence-based framework for reducing dynamic lung strain and preventing postoperative pulmonary complications. By translating complex respiratory physiology into actionable clinical metrics, Orlando has bridged a critical gap between research and operating room practice. Her findings are increasingly influential in shaping ventilation protocols for obese patients and those undergoing prolonged laparoscopic procedures, marking her as an emerging leader in perioperative lung protection.
Research Focus
Key Achievements
Top Papers
- 1