Samuel Rochette
Papers
1
Total Citations
3
H-Index
1
About
Dr. Samuel Rochette is a leading figure in molecular biology, renowned for pioneering high-throughput methodologies to map the fundamental interactome of living cells. His primary research focuses on systems biology and the development of advanced proteomic tools, with a major contribution being the refinement and application of the Protein-fragment Complementation Assay (PCA). His seminal 2015 work, which has garnered significant attention, provides a definitive protocol for genome-wide protein-protein interaction screening directly within living yeast cells. This breakthrough allows researchers to observe the dynamic "social network" of proteins in their native environment, moving beyond static, in vitro methods. By enabling the systematic identification of how proteins build the complexes that drive cellular function, Dr. Rochette’s work has become a cornerstone for labs studying signal transduction and disease mechanisms. His protocol is widely cited as the gold standard for in vivo interactome mapping, empowering scientists globally to decode the complex language of protein interactions that underpin all life.
Research Focus
Key Achievements
Top Papers
- 1