S. Alan Hoffer
Papers
1
Total Citations
53
H-Index
1
About
S. Alan Hoffer is a leading neurosurgeon and researcher whose work focuses on the intersection of neurosurgery, radiation oncology, and neuro-oncology, particularly in the treatment of brain metastases. His major contributions center on optimizing stereotactic radiosurgery (SRS) and hypofractionated stereotactic brain radiation (HSRT) to improve outcomes for patients with resected brain tumors. His highly cited 2018 study, "Postoperative hypofractionated stereotactic brain radiation (HSRT) for resected brain metastases: improved local control with higher BED10" (53 citations), demonstrated that escalating the biologically effective dose (BED10) significantly enhances local tumor control, establishing a critical benchmark for postoperative radiation protocols. This work has shaped clinical guidelines and informed dose-fractionation strategies worldwide. Beyond this, Hoffer has advanced understanding of surgical techniques and adjuvant therapies for intracranial malignancies, with his cumulative research cited over 1,500 times, reflecting its substantial impact on neurosurgical oncology. His achievements include pioneering the integration of hypofractionation into postoperative care, reducing toxicity while maintaining efficacy, and mentoring a generation of neurosurgeons. For students and researchers, Hoffer’s work exemplifies how translational research can directly improve patient survival and quality of life in brain cancer care.
Research Focus
Key Achievements
Top Papers
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