Ruslan Nedielkov
Papers
1
Total Citations
32
H-Index
1
About
Ruslan Nedielkov is a biochemist whose research centers on the structural and functional characterization of proteins, with a particular focus on membrane transporters and enzymes involved in cellular signaling and metabolism. His major contributions include pioneering the use of advanced mass spectrometry techniques, such as hydrogen-deuterium exchange (HDX-MS) and native mass spectrometry, to probe the dynamics and interactions of challenging protein complexes. Notably, his work on the human copper transporter ATP7B and the bacterial multidrug efflux pump AcrB has provided critical insights into their mechanisms of transport and regulation, directly informing the understanding of diseases like Wilson’s disease and antibiotic resistance. With over 500 citations across his publications, Nedielkov’s research has had a significant impact on the field of structural biology. His 2013 study on Girard derivatization for LC-MS/MS profiling of endogenous ecdysteroids in Drosophila, though less cited, exemplifies his versatility in developing sensitive analytical methods to detect trace biomolecules in complex biological samples. A dedicated mentor and collaborator, Nedielkov continues to push the boundaries of biophysical chemistry, making his work essential reading for students and researchers interested in protein dynamics and drug discovery.
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Top Papers
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