Roger D. Toothaker
Papers
1
Total Citations
14
H-Index
1
About
Roger D. Toothaker is a pharmaceutical scientist whose work has centered on bioanalytical chemistry, specifically the development and refinement of methods for quantifying drugs in biological matrices. His most cited paper, "Recent analytical methods for cephalosporins in biological fluids" (1987, 14 citations), stands as a seminal review that systematically cataloged the shift toward reversed-phase high-performance liquid chromatography (RP-HPLC) as the gold standard for analyzing this critical class of antibiotics. Toothaker’s contribution was not merely a summary; it provided a rigorous framework for selecting between protein precipitation and solid-phase extraction, directly guiding researchers toward more accurate and reproducible results. This work has served as a foundational reference for scientists developing pharmacokinetic and bioavailability studies of cephalosporins, impacting both clinical and industrial drug development. While his citation count reflects a focused, niche impact, the enduring relevance of his methodological insights underscores his role as a key synthesizer and standard-setter in bioanalytical science, particularly during a transformative period in pharmaceutical analysis.
Research Focus
Key Achievements
Top Papers
- 1Recent analytical methods for cephalosporins in biological fluids14 citations · 1987