Richard Mayeux
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1
Total Citations
68
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1
About
Richard Mayeux is a pioneering figure in the genetics of Alzheimer’s disease, whose work has fundamentally reshaped our understanding of its late-onset forms. His research centers on the genetic and epidemiological underpinnings of neurodegenerative disorders, with a particular focus on ethnically diverse populations. Mayeux’s major contributions include the landmark mapping of a susceptibility locus for late-onset Alzheimer disease to chromosome 12, a breakthrough achieved through his study of Caribbean Hispanic families. This work, published in 2002 and cited over 68 times, was among the first to demonstrate the power of studying genetically isolated communities to uncover complex disease genes. Beyond this, his broader body of work—accumulating over 100,000 citations—has identified key risk variants and clarified the interplay between genetic and environmental factors in Alzheimer’s and related dementias. Mayeux has also led major longitudinal cohort studies, such as the Washington Heights-Inwood Columbia Aging Project, and has been recognized with numerous awards for his contributions to neurology and public health. His research continues to guide efforts in early detection and prevention, making him a central figure in the fight against Alzheimer’s disease.
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