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About

Pete Gagnon is a specialist in downstream bioprocessing, with a particular focus on chromatographic purification of biopharmaceuticals, most notably monoclonal antibodies (mAbs). His research has centered on hydroxyapatite (HA) chromatography — a calcium phosphate-based stationary phase — as a powerful yet underutilized tool for achieving high-purity therapeutic proteins at industrial scale. Gagnon's most influential contribution, "Monoclonal antibody purification with hydroxyapatite" (2009), has garnered 69 citations and helped establish HA chromatography as a viable, complementary technology to Protein A affinity purification in mAb manufacturing workflows. His subsequent work pushed the field further by demonstrating that selective desorption strategies on ceramic hydroxyapatite (CHT) could effectively separate monomeric mAb from aggregates and other challenging post-Protein A impurities — a critical quality concern in biopharmaceutical development. His exploration of unique selectivity windows using selective displacers, eluents, and mobile phase modifiers expanded the toolkit available to purification scientists seeking fine-tuned control over separation outcomes. Across his published work, Gagnon has helped bridge the gap between academic chromatography research and practical biomanufacturing, offering strategies that are both scientifically rigorous and industrially actionable.