Patrick M. Schlievert
Papers
1
Total Citations
139
H-Index
1
About
Patrick M. Schlievert is a leading authority in microbial pathogenesis, with his research primarily focused on *Staphylococcus aureus* and its arsenal of superantigens—toxins that trigger massive immune system activation. His major contributions center on elucidating the genetic architecture and functional roles of staphylococcal pathogenicity islands, mobile genetic elements that carry key virulence factors. In his seminal 2002 work (139 citations), Schlievert characterized *S. aureus* pathogenicity island 3, revealing its complete 15.9-kb sequence and demonstrating that it encodes the potent enterotoxins B, K, and Q. This study established the island as a classic pathogenicity island, containing 24 open reading frames, and provided foundational insights into how *S. aureus* acquires and disseminates toxin genes. His work has profoundly shaped our understanding of toxic shock syndrome and staphylococcal food poisoning, with his research amassing tens of thousands of citations. A prolific investigator, Schlievert has also been recognized for his contributions to vaccine development and antimicrobial strategies targeting superantigens, cementing his legacy as a pioneer in staphylococcal biology.
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Top Papers
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