Pasi Hirvikoski
Papers
1
Total Citations
20
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1
About
Pasi Hirvikoski is a pathologist whose research sits at the intersection of diagnostic surgical pathology and molecular biology, with a particular focus on improving tissue preservation methods for prostate cancer research. His most cited work, a 2017 study on the feasibility of PAXgene fixation for prostate tissue, directly addresses a critical bottleneck in translational oncology: the need to preserve both high-quality morphology for diagnosis and intact nucleic acids for molecular analysis. By systematically comparing fresh frozen, formalin-fixed paraffin-embedded (FFPE), and PAXgene-fixed paraffin-embedded (PFPE) preparations, Hirvikoski demonstrated that PAXgene fixation can bridge the gap between routine clinical workflows and cutting-edge genomic research. This contribution, cited 20 times, is foundational for researchers seeking to integrate molecular phenotyping into standard diagnostic pathology. His work underscores a commitment to advancing precision medicine by ensuring that tissue samples used for diagnosis can also yield reliable molecular data, thereby accelerating discoveries in prostate cancer biology and biomarker development.
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