Niklas Magnell
Papers
1
Total Citations
14
H-Index
1
About
Niklas Magnell is a researcher whose work bridges analytical chemistry and pharmaceutical science, with a primary focus on bioanalytical method development for drug metabolism and pharmacokinetics. His most cited study, "Determination of ximelagatran, melagatran and two intermediary metabolites in plasma by mixed-mode solid phase extraction and LC–MS/MS" (2007, 14 citations), exemplifies his expertise in advancing liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques. In this work, Magnell developed a robust, sensitive method for quantifying the anticoagulant ximelagatran and its active metabolite melagatran, along with two intermediate metabolites, using mixed-mode solid phase extraction. This contribution is notable for its practical impact on clinical and preclinical drug monitoring, enabling precise measurement of these compounds in plasma—a critical step for safety and efficacy studies. While his citation count reflects a focused, specialized audience, Magnell’s methodological rigor and attention to detail have made his work a reference point for researchers tackling similar challenges in bioanalysis. His achievements underscore the importance of reliable analytical tools in drug development, offering a model for students and scientists aiming to refine pharmacokinetic assessments.
Research Focus
Key Achievements
Top Papers
- 1