Nachi Palaniappan
Papers
1
Total Citations
18
H-Index
1
About
Dr. Nachi Palaniappan is a leading clinical researcher in head and neck oncology, with a focused expertise in de-escalation strategies for human papillomavirus (HPV)-positive oropharyngeal cancer. Her major contribution is advancing risk-stratified, reduced-intensity treatment protocols designed to preserve excellent survival outcomes while minimizing the severe, long-term toxicities associated with conventional therapies. She is the principal investigator of the landmark PATHOS trial (Phase II/III), a practice-shaping study that investigates tailoring adjuvant treatment intensity after transoral surgery based on pathological risk features. This work, cited 18 times, addresses the critical need to improve quality of life for the growing population of younger, healthier HPV-positive patients. Dr. Palaniappan’s research directly challenges the one-size-fits-all paradigm, aiming to spare patients from unnecessary chemotherapy and radiation toxicity without compromising cure rates. Her contributions are pivotal in the ongoing shift toward personalized, function-preserving care in head and neck cancer, making her a key voice in defining the future standard of treatment for this disease.
Research Focus
Key Achievements
Top Papers
- 1