Papers
1
Total Citations
24
H-Index
1
About
My-Hanh Lam has made significant contributions to the field of lipid enzymology, with a particular focus on endothelial lipase (EL), a key regulator of high-density lipoprotein (HDL) cholesterol metabolism. Her most cited work, "Fluorogenic substrates for high-throughput measurements of endothelial lipase activity" (2006, 24 citations), introduced innovative fluorescent Bodipy-based substrates that enabled rapid, sensitive, and scalable assays for EL activity. This methodological breakthrough was critical for advancing drug discovery efforts aimed at identifying small molecule inhibitors that specifically target EL, offering a potential therapeutic avenue for modulating HDL cholesterol levels in cardiovascular disease. Lam’s work bridged the gap between fundamental lipid biology and translational pharmacology, providing researchers with a practical tool to screen for EL inhibitors efficiently. Her contributions are particularly notable for their impact on high-throughput screening technologies, which have accelerated the development of targeted therapies. With a career focused on assay development and enzyme characterization, My-Hanh Lam stands out as a researcher whose technical innovations have enabled deeper insights into lipid metabolism and opened new pathways for treating dyslipidemia.
Research Focus
Key Achievements
Top Papers
- 1